The Methyl B12 seems to be good, I feel it because it helps me sleep and seem to help with cell growth for an injury I had to my hand. I also like that this is not a lozenge which is less stable because they quickly absorb moisture and B12 breaks down from that, especially if you don't want to take this every day or you want to have a time off period with it. Also, since its not flavored and sweeten your mouth won't salivate excessively if you allow to absorb there first. Lozenges just wash it down into your stomach too quickly before it has a chance to have much contact with the mucosa surface. Now is the only brand that seems to offer the capsule option. My only gripe with Now is that they use that flip top cap which can't be tightly twisted on like conventional caps, so your basically letting air/moisture in and out with every change in room temperature since air expands and contracts as it warms up or cools down. What that means is if you buy a Now product and want to use it over a longer time like a year or two, if you aren't taking it every day like they expect you to, then you can't count on the stability or freshness of the actives. I know from the natural products industry standards/testing that shelf life is only based on "unopened" bottles or packaging and is no longer valid after you break the seal/open it. At least with other lids you can tighten them pretty good to minimize air getting in or out but not with the Now bottles. What I have to do is transfer the contents to a another empty bottle with a regular screw cap and then label the product, brand, and exp. date on the new bottle to ensure it doesn't break down as fast from oxygen and humidity. Well it is true that every time you open the bottle to take out a capsule then you let some air in, but with a loose lid your allowing constant air and especially humidity access which is probably the worst part of accelerated break down of the actives. The desiccant pack might help a little at first but becomes worthless since the cap can't be tightened because they only have a limited capacity to absorb moisture. A last concern is that they do not have a warning on the label about the well documented risk of higher B12 supplementation having a risk of lung and colon adenoma. For those with a personal or family history this would be a serious risk or concern.
